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Gastroenterology 8 min read Undergraduate & Postgraduate

Cirrhosis: Complications You Must Be Ready to Discuss in Exams

A complication-based approach to ascites, varices, encephalopathy, spontaneous bacterial peritonitis and hepatocellular carcinoma surveillance.

Exam-oriented educational summary · Updated 10 September 2026

Typical exam stem

A patient with known cirrhosis presents with increasing abdominal distension and confusion. How would you assess the decompensation?

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1. Sixty-second answer plan

1:00

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2. Section checklist

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3. Exam-pearl flashcards

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4. Viva drill

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Question 1 of 30 confident

What commonly precipitates hepatic encephalopathy?

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1

Think decompensation, trigger and complication

Cirrhosis can remain compensated for years before ascites, variceal bleeding, encephalopathy or jaundice marks decompensation. In an exam, state the likely complication, assess severity and search for a trigger such as infection, GI bleeding, dehydration, constipation, medication effects, alcohol use or portal-vein thrombosis.

2

Ascites and spontaneous bacterial peritonitis

  • New, worsening or hospitalised ascites commonly warrants diagnostic paracentesis.
  • Send cell count and differential, culture and relevant biochemistry according to local practice.
  • Suspect spontaneous bacterial peritonitis with abdominal pain, fever, encephalopathy, hypotension, AKI or unexplained deterioration.
  • Management combines appropriate antimicrobial therapy, assessment for albumin use according to protocol, and review of renal function and diuretics.
3

Other exam-critical complications

  • Variceal bleeding: resuscitation, vasoactive therapy, antibiotics and urgent endoscopic treatment.
  • Hepatic encephalopathy: identify and treat precipitants while reducing gut-derived nitrogen load according to local protocol.
  • Hepatorenal syndrome: recognise worsening renal function in advanced liver disease after excluding other causes of AKI.
  • Hepatocellular carcinoma surveillance and assessment for liver transplantation should be considered according to stage and prognosis.

Guideline source for further reading

This page is an original exam-revision summary. For clinical decisions, use current local protocols and the primary guidance below.

Educational use: This material is designed for examination revision and does not replace patient-specific clinical judgement, local treatment protocols or specialist advice.